The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2008
Filed:
Jan. 15, 2003
Applicants:
Donald Choy Chang, Kowloon, HK;
Qian (Kathy) Luo, Kowloon, HK;
Inventors:
Donald Choy Chang, Kowloon, HK;
Qian (Kathy) Luo, Kowloon, HK;
Assignee:
Hong Kong University of Science and Technology, Hong Kong SAR, HK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
Isolated nucleic acids encoding a fluorescent protein construct that detect apoptosis are disclosed. The isolated nucleic acids contain a donor-acceptor pair of green fluorescent proteins and a peptide linker containing a substrate sequence encoding a cleavage site of a caspase. The linker is flanked with at least one glycine pair. Expression constructs, isolated host cells and gene delivery vehicles containing these isolated nucleic acids are also disclosed.