The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2008

Filed:

Feb. 02, 2004
Applicants:

Jianwu Dai, Boston, MA (US);

Eugene Bell, Boston, MA (US);

Vladimir Russakovsky, Boston, MA (US);

Inventors:

Jianwu Dai, Boston, MA (US);

Eugene Bell, Boston, MA (US);

Vladimir Russakovsky, Boston, MA (US);

Assignee:

TEI Biosciences, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 1/02 (2006.01); A61F 2/00 (2006.01); C12N 11/02 (2006.01); C12N 5/06 (2006.01); C12N 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue, particularly fetal or neo-natal tissue, to chemical and mechanical processing. The process includes, but is not limited to, harvesting the tissue, optionally extracting growth and differentiation factors from the tissue, inactivating infective agents of the tissue, mechanically expressing undesirable components from the tissue, delipidizing the tissue, washing the tissue, optionally drying the tissue, optionally cross-linking the tissue not necessarily in the order described. The resulting product, EBM, is characterized by its microbial, fungal, viral and prion inactivated state. EBM is strong, bioremodelable, drapable and does not undergo calcification. EBM supplants previous inventions because of its unique method of preparation and broad applicability in tissue reengineering.


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