The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2008

Filed:

Mar. 31, 2006
Applicants:

Camellia W. Adams, Mountainview, CA (US);

Brigitte Devaux, Redwood City, CA (US);

Dan L. Eaton, San Rafael, CA (US);

Philip E. Hass, Moss Beach, CA (US);

J. Kevin Judice, Montara, CA (US);

Daniel Kirchhofer, Los Altos, CA (US);

Shelley Suggett, San Francisco, CA (US);

Inventors:

Camellia W. Adams, Mountainview, CA (US);

Brigitte Devaux, Redwood City, CA (US);

Dan L. Eaton, San Rafael, CA (US);

Philip E. Hass, Moss Beach, CA (US);

J. Kevin Judice, Montara, CA (US);

Daniel Kirchhofer, Los Altos, CA (US);

Shelley Suggett, San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/53 (2006.01); C12P 21/04 (2006.01); C12P 21/08 (2006.01); C07K 16/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides for the isolation, identification, synthesis, expression and purification of antibodies reactive with factor IX (FIX)/factor IXa (IXa). In particular aspects, the invention provides human antibodies reactive with the human FIX Gla domain. The invention further provides compositions especially pharmaceutical compositions, articles of manufacture, and methods of inhibiting the activation of FIX and inhibiting FIX/IXa dependent coagulation.


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