The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2008

Filed:

Mar. 14, 2003
Applicants:

Jayasree Vasudevan, Anaheim, CA (US);

Liming Wang, Irvine, CA (US);

Xiaoxia Liu, Tustin, CA (US);

Kwok-yin Tsang, Irvine, CA (US);

Yang-dar Yuan, Irvine, CA (US);

Roshantha A. Chandraratna, Laguna Hills, CA (US);

Inventors:

Jayasree Vasudevan, Anaheim, CA (US);

Liming Wang, Irvine, CA (US);

Xiaoxia Liu, Tustin, CA (US);

Kwok-Yin Tsang, Irvine, CA (US);

Yang-Dar Yuan, Irvine, CA (US);

Roshantha A. Chandraratna, Laguna Hills, CA (US);

Assignee:

Allergan, Inc., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); C07D 311/76 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of the formula where the variables are defined in the specification have cytochrome P450RAI-1 and P450RAI-2 inhibitory activity, and are suitable for treatment of mammals with conditions which are treatable with retinoids, or which are controlled by or responsive to the organism's native retinoic acid. Formulations containing the compounds of the invention can also be co-administered with retinoids and/or Vitamin A to enhance or prolong the effects of medications containing retinoids, Vitamin A, or of the organism's native retinoic acid.


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