The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2008
Filed:
Jul. 14, 2005
Dawn Alisa Brooks, Indianapolis, IN (US);
Scott Eugene Conner, Elizabethtown, IN (US);
Samuel James Dominianni, Indianapolis, IN (US);
Alexander Glenn Godfrey, Mooresville, IN (US);
Lynn Stacy Gossett, Indianapolis, IN (US);
Christopher John Rito, Martinsville, IN (US);
Allie Edward Tripp, Indianapolis, IN (US);
Alan M. Warshawsky, Carmel, IN (US);
Leonard Larry Winneroski, Jr., Greenwood, IN (US);
Guoxin Zhu, Noblesville, IN (US);
Dawn Alisa Brooks, Indianapolis, IN (US);
Scott Eugene Conner, Elizabethtown, IN (US);
Samuel James Dominianni, Indianapolis, IN (US);
Alexander Glenn Godfrey, Mooresville, IN (US);
Lynn Stacy Gossett, Indianapolis, IN (US);
Christopher John Rito, Martinsville, IN (US);
Allie Edward Tripp, Indianapolis, IN (US);
Alan M. Warshawsky, Carmel, IN (US);
Leonard Larry Winneroski, Jr., Greenwood, IN (US);
Guoxin Zhu, Noblesville, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Compounds represented by the following structural formula (I), and pharmaceutically acceptable salts, solvates and hydrates thereof, wherein R1 is an unsubstituted or substituted aryl, heteroaryl, cycloalkyl, aryl-alkyl, heteroaryl-alkyl or cycloalkyl-alkyl, R2 is H, alkyl or haloalkyl, the polymethylene chain (II), is saturated or may contain a carbon-carbon double bond, while n is 2, 3, 4, W is O or S, Y is an unsubstituted phenylene, naphthylene or 1, 2, 3, 4 tetrahydronaphthylene, R3 is II, alkyl or haloalkyl, R4 is II, alkyl, haloalkyl or a substituted or unsubstituted benzyl, are useful for modulating a peroxisome proliferator activated receptor, particularly in the treatment of diabetes mellitus.