The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2008
Filed:
Jan. 24, 2001
Diethard Mattanovich, Vienna, AT;
Hermann Katinger, Vienna, AT;
Hubertus Hohenblum, Vienna, AT;
Stefan Naschberger, Vienna, AT;
Robert Weik, Vienna, AT;
Diethard Mattanovich, Vienna, AT;
Hermann Katinger, Vienna, AT;
Hubertus Hohenblum, Vienna, AT;
Stefan Naschberger, Vienna, AT;
Robert Weik, Vienna, AT;
Polymun Scientific Immunbiologische Forschung GmbH, Vienna, AT;
Abstract
The present invention relates to a method for the manufacture and purification of recombinant trypsinogen and trypsin inand yeast, using high yield expression vectors with and without secretion leader sequences. The invention further relates to an improved method and apparatus for carrying out protein refolding specifically useful for processing trypsinogen that has accumulated intracellularly in the form of inclusion bodies.