The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2008
Filed:
Aug. 30, 2004
Applicants:
David B. Rozema, Madison, WI (US);
Darren Wakefield, Fitchburg, WI (US);
Inventors:
David B. Rozema, Madison, WI (US);
Darren Wakefield, Fitchburg, WI (US);
Assignee:
Mirus Bio Corporation, Madison, WI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 65/21 (2006.01); A61K 47/18 (2006.01);
U.S. Cl.
CPC ...
Abstract
Described are ortho carboxy phenol derived acetals and compositions containing ortho carboxy phenol derived acetals which are useful for delivering biologically active compounds to cells. The acetals can be used to reversibly link up to three different molecules and have rapid hydrolysis kinetics in conditions which are present in a cell as well as in vivo. Cleavage of the acetal enhances delivery of the biologically active compound.