The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2008

Filed:

Apr. 25, 2003
Applicants:

Howard C. H. Kuo, Plainfield, NJ (US);

Michelle B. Ayer, Fanwood, NJ (US);

Prasun K. Chakravarty, Edison, NJ (US);

Peter T. Meinke, Plainfield, NJ (US);

William H. Parsons, Belle Mead, NJ (US);

Sriram Tyagarajan, Edison, NJ (US);

Inventors:

Howard C. H. Kuo, Plainfield, NJ (US);

Michelle B. Ayer, Fanwood, NJ (US);

Prasun K. Chakravarty, Edison, NJ (US);

Peter T. Meinke, Plainfield, NJ (US);

William H. Parsons, Belle Mead, NJ (US);

Sriram Tyagarajan, Edison, NJ (US);

Assignee:

Merck & Co. Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/425 (2006.01); C07D 277/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds are sodium channel blockers; pharmaceutical compositions that include an effective amount of the aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds and a pharmaceutically acceptable carrier, and a method of treatment of acute pain, chronic pain, visceral pain, inflammatory pain, or neuropathic pain, as well as initable bowel syndrome, Cnohns disease, epilepsy, partial and generalized tonic seizures, multiple sclerosis, bipolar depression, and tachy-arrhythmias by the administration of an effective amount of aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds are described.


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