The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7348025 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 25, 2008

Filed:

Sep. 16, 2003
Applicants:

J. Vernon Knight, Houston, TX (US);

Nadezhda Koshkina, Houston, TX (US);

Brian Gilbert, Houston, TX (US);

Claire F. Verschraegen, Albuquerque, NM (US);

Inventors:

J. Vernon Knight, Houston, TX (US);

Nadezhda Koshkina, Houston, TX (US);

Brian Gilbert, Houston, TX (US);

Claire F. Verschraegen, Albuquerque, NM (US);

Assignee:

Research Development Foundation, Carson City, NV (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 9/127 (2006.01); A61L 9/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein is a method of treating primary lung cancer or metastatic cancer to the lung in an individual by delivering at least once to the respiratory tract of the individual via inhalation a nebulized liposomal aerosol comprising a dilauroylphosphatidylcholine liposome containing camptothecin or a derivative thereof in an amount sufficient to deliver a pharmacologically effective dose of the camptothecin or its derivative to treat the cancer. Also provided is a nebulized liposomal aerosol comprising the DLPC containing the camptothecin or its derivative and a method of making the liposome-drug comprising the aerosol.


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