The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2008
Filed:
Jan. 15, 2004
Raymond A. Dwek, Oxford, GB;
Terence D. Butters, Oxford, GB;
Mylvaganam Jeyakumar, Oxford, GB;
Frances Mary Platt, Oxford, GB;
David Priestman, Oxford, GB;
Raymond A. Dwek, Oxford, GB;
Terence D. Butters, Oxford, GB;
Mylvaganam Jeyakumar, Oxford, GB;
Frances Mary Platt, Oxford, GB;
David Priestman, Oxford, GB;
Actelion Pharmaceuticals Ltd, Allschwil, CH;
Abstract
A method for treating a glycolipid storage-related disorder, comprising administering a therapeutically effective amount of an inhibitor of glycolipid synthesis in combination with an agent capable of increasing the rate of glycolipid degradation or in combination with bone marrow transplantation. Inhibitors of glycolipid synthesis include N-butyldeoxynojirimycin (NB-DNJ), N-butyldeoxygalactonojirimycin (NB-DGJ) or N-nonyldeoxynojirimycin (NN-DNJ). Glycolipid storage-related disorders include Gaucher disease, Sandhoff's disease, Fabry's disease, Tay-Sach's disease, Niemann-Pick C storage disease, GM1 gangliosidosis, genetic disorders in which neuronal glycolipid accumulation contributes to disease pathology.