The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2008

Filed:

Nov. 12, 2004
Applicant:

OM P. Goel, Ann Arbor, MI (US);

Inventor:

Om P. Goel, Ann Arbor, MI (US);

Assignee:

SSV Therapeutics, Inc., Ann Arbor, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses novel dual prodrug compositions of Formula 1, wherein A is a single bond, —O—, or —CH—; m and n vary from 0 to 15; p and q vary from 0 to 4; B is a single bond or —CRR; D is selected from the group consisting —COR, —OR, —OCOR, —SOR, —SONH, —OPO(OR)(OR), —OPO(OR)(NH), —OPO(OR)—O—PO(OR)(OR), Rto Rare various substituents selected to optimize the physicochemical and biological properties such as, lipophilicity, toxicity, bioavailability, and pharmacokinetics of compounds of Formula 1. These compounds are useful for the treatment of various cardiovascular and neurological disorders.


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