The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2008
Filed:
Feb. 09, 2005
Dawn Alisa Brooks, Indianapolis, IN (US);
Alexander Glenn Godfrey, Mooresville, IN (US);
Sarah Beth Jones, Greenwood, IN (US);
James Ray Mccarthy, Zionsville, IN (US);
Christopher John Rito, Martinsville, IN (US);
Leonard Larry Winneroski, Greenwood, IN (US);
Yanping Xu, Fishers, IN (US);
Dawn Alisa Brooks, Indianapolis, IN (US);
Alexander Glenn Godfrey, Mooresville, IN (US);
Sarah Beth Jones, Greenwood, IN (US);
James Ray McCarthy, Zionsville, IN (US);
Christopher John Rito, Martinsville, IN (US);
Leonard Larry Winneroski, Greenwood, IN (US);
Yanping Xu, Fishers, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Compounds represented by the following structural formula (I), and pharmaceutically acceptable salts, solvates and hydrates thereof, wherein: n is 2, 3, or 4 and W is CH, CH(OH), C(O) or O; R1 is an unsubstituted or substituted aryl, heteroaryl, cycloalkyl, heterocycloalkyl, aryl-alkyl, heteroaryl-alkyl, cycloalkyl-alkyl, or t-butyl; R2 is H, alkyl, haloalkyl or phenyl; Y is an unsubstituted or substituted thiophen-2,5-diyl or phenylene; R3 is alkyl or haloalkyl; R4 is a substituted or unsubstituted phenyl, naphthyl, 1,2,3,4-tetrahydronaphthyl, quinolyl, pyridyl or benzo[1,3]dioxol-5-yl group; and R5 is H, alkyl, or aminoalkyl; are useful for modulating a peroxisome proliferator activated receptor, particularly in the treatment of diabetes mellitus.