The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2008

Filed:

Nov. 05, 2003
Applicants:

Sumit Chanda, La Jolla, CA (US);

Suhaila White, San Diego, CA (US);

John B. Hogenesch, Encinitas, CA (US);

Jeremy S. Caldwell, Cardiff, CA (US);

Inventors:

Sumit Chanda, La Jolla, CA (US);

Suhaila White, San Diego, CA (US);

John B. Hogenesch, Encinitas, CA (US);

Jeremy S. Caldwell, Cardiff, CA (US);

Assignee:

IRM LLC, , BM;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides novel AP-1 modulatory polypeptides. The invention also provides methods for screening modulators of AP-1 transcription factor activities. The methods comprise first screening test agents for modulators of an AP-1-modulatory polypeptide and then further screening the identified modulating agents for modulators of AP-1 transcription factor activities. The invention further provides methods and pharmaceutical compositions for modulating AP-1 transcription factor activities in a cell and for treating diseases and conditions mediated by abnormal cellular proliferation.


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