The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2008
Filed:
Jun. 21, 2004
Eric J. Hansen, Plano, TX (US);
Christoph Aebi, Gasel, CH;
Leslie D. Cope, Mesquite, TX (US);
Isobel Maciver, Cottage Grove, WI (US);
Michael J. Fiske, Rochester, NY (US);
Ross A. Fredenburg, Rochester, NY (US);
Eric J. Hansen, Plano, TX (US);
Christoph Aebi, Gasel, CH;
Leslie D. Cope, Mesquite, TX (US);
Isobel Maciver, Cottage Grove, WI (US);
Michael J. Fiske, Rochester, NY (US);
Ross A. Fredenburg, Rochester, NY (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Wyeth Holdings Corporation, Madison, NJ (US);
Abstract
The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two proteins and comprises an epitope that is recognized by the MAb 17C7. One or more than one of these species may aggregate to form the very high molecular weight form (i.e. greater than 200 kDa) of the UspA antigen. Compositions and both diagnostic and therapeutic methods for the treatment and study ofare disclosed.