The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2008
Filed:
Aug. 11, 2004
John H. Van Duzer, Georgetown, MA (US);
Arthur F. Michaelis, Devon, PA (US);
William B. Geiss, Athens, NY (US);
Douglas G. Stafford, Niskayuna, NY (US);
Joseph Raker, Delmar, NY (US);
John H. van Duzer, Georgetown, MA (US);
Arthur F. Michaelis, Devon, PA (US);
William B. Geiss, Athens, NY (US);
Douglas G. Stafford, Niskayuna, NY (US);
Joseph Raker, Delmar, NY (US);
ActivBiotics, Inc., Lexington, MA (US);
Abstract
The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3'-hydroxy analogs, 4′- and/or 6′ halo and/or alkoxy analogs, and various 5′ substituents that incorporate a cyclic amine moiety.