The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2008
Filed:
Feb. 06, 2004
Feng Xu, Staten Island, NY (US);
Matthew M Bio, London, GB;
Cameron Cowden, Hoddesdon, GB;
Kimberly A. Petrillo, Philadelphia, PA (US);
J. Michael Williams, Hillsborough, NJ (US);
Chunhua Yang, Edison, NJ (US);
Marjorie See Waters, Cranbury, NJ (US);
Feng Xu, Staten Island, NY (US);
Matthew M Bio, London, GB;
Cameron Cowden, Hoddesdon, GB;
Kimberly A. Petrillo, Philadelphia, PA (US);
J. Michael Williams, Hillsborough, NJ (US);
Chunhua Yang, Edison, NJ (US);
Marjorie See Waters, Cranbury, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
A process is provided for the preparation of branched-chain ribonucleosides of formula (I): from the 1,2-anhydroderivatives of formula (II). wherein PG is a hydroxyl protecting group, B is a purine or pyrimidine nucleobase, and Ris Calkyl. The compounds of formula (I) are inhibitors of HCV polymerase useful in the treatment of HCV infection.