The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2008
Filed:
Feb. 22, 2005
Applicants:
Ambrose L. Cheung, Hanover, NH (US);
Adhar Manna, Lebanon, NH (US);
Inventors:
Ambrose L. Cheung, Hanover, NH (US);
Adhar Manna, Lebanon, NH (US);
Assignee:
Trustees of Dartmouth College, Hanover, NH (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 39/00 (2006.01); A61K 39/09 (2006.01); A61K 39/085 (2006.01);
U.S. Cl.
CPC ...
Abstract
A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants inis provided. Methods for modulating the expression of sarA and virulence determinants are also provided. A preferred embodiment of the present invention provides structural information relating to the gene product and enables the identification and formulation of lead compounds and reducements for treating and preventing infections byand related bacteria.