The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2008

Filed:

Feb. 28, 2003
Applicants:

Stanley Dawes Chamberlain, Durham, NC (US);

Mui Cheung, Durham, NC (US);

Holly Kathleen Emerson, Durham, NC (US);

Neil W. Johnson, Collegeville, PA (US);

Kristen Elizabeth Nailor, Durham, NC (US);

Douglas Mccord Sammond, Durham, NC (US);

Marcus Semones, Collegeville, PA (US);

Inventors:

Stanley Dawes Chamberlain, Durham, NC (US);

Mui Cheung, Durham, NC (US);

Holly Kathleen Emerson, Durham, NC (US);

Neil W. Johnson, Collegeville, PA (US);

Kristen Elizabeth Nailor, Durham, NC (US);

Douglas McCord Sammond, Durham, NC (US);

Marcus Semones, Collegeville, PA (US);

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorneys:
Int. Cl.
CPC ...
C07D 239/48 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); A61K 31/506 (2006.01); A61K 31/4184 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.


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