The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2008
Filed:
Sep. 30, 2004
Travis Mickle, Blacksburg, VA (US);
Suma Krishnan, Blacksburg, VA (US);
James Scott Moncrief, Chrisitansburg, VA (US);
Christopher Lauderback, Blacksburg, VA (US);
Christal Miller, Charlottesville, VA (US);
Travis Mickle, Blacksburg, VA (US);
Suma Krishnan, Blacksburg, VA (US);
James Scott Moncrief, Chrisitansburg, VA (US);
Christopher Lauderback, Blacksburg, VA (US);
Christal Miller, Charlottesville, VA (US);
New River Pharmaceuticals Inc., Radford, VA (US);
Abstract
The present invention decreases the potential for abuse of opioids, particularly hydrocodone, by covalent modification. The invention provides methods of delivering hydrocodone as conjugates that release the hydrocodone following oral administration while being resistant to abuse by circuitous routes such as intravenous ('shooting') injection and intranasal administration ('snorting'). Further, hydrocodone compositions of the invention are resistant to oral abuse as well, since release of the hydrocodone at suprapharmacological doses reaches saturation.