The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2008
Filed:
Nov. 18, 2002
Applicants:
Sara Arab, North York, CA;
Clifford A. Lingwood, Toronto, CA;
Aye-aye Khine, Concord, CA;
Inventors:
Assignee:
Hospital for Sick Children Research and Development Limited Partnership, Toronto, Ontario, CA;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/245 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 38/16 (2006.01); A61K 31/7088 (2006.01); C12N 5/00 (2006.01); C12N 15/87 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
Hybrid compounds comprising a first domain and a second domain are provided. The first domain and the second domain are preferably covalently linked, and the first domain comprises a domain which is capable of specific binding to Gb; and the second domain comprising a moiety selected from the group consisting of drug moiety, a nucleic acid, a probe, a polypeptide, and a hook, with the proviso that the second domain is not a verotoxin or a fragment thereof. Methods of preparing and using the hybrid compounds are also provided.