The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7335677 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 26, 2008

Filed:

Oct. 23, 2002
Applicants:

David M. Evans, Southampton, GB;

Doreen M. Ashworth, Southampton, GB;

Inventors:

David M. Evans, Southampton, GB;

Doreen M. Ashworth, Southampton, GB;

Assignee:

Ferring B.V., Hoofddorp, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 403/12 (2006.01); A61K 31/4025 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel compounds that are inhibitors of one or most post-proline cleaving proteases, e.g. dipeptidyl peptidase IV, according to general formula (1). Ris H or CN, Xis O, S, CH, CHF, CF, CH(CH), C(CH)or CH(CN), and b is 1 or 2. Gis H or a group according to the formula —CH—X—(CH)-Gand Gis H or a group according to the formula —CH—(CH9-G, provided that one of Gand Gis H and the other is not H. Xis O, S, or CH, and a is 0, 1 or 2, provided that when a is 1 then Xis CH. Gis a group according to one of general formulae 2-4, where the variables have meaning given in the description. The compounds are useful in the treatment of i.a. type 2 diabetes and impaired glucose tolerance


Find Patent Forward Citations

Evans, David. (2008). Inhibitors of dipeptidyl peptidase iv (U.S. Patent No. 7335677). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7335677

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