The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2008
Filed:
Feb. 14, 2003
Hubert Jan Jozef Loozen, Oss, NL;
Markus Wagener, Oss, NL;
Gerrit Veeneman, Oss, NL;
Eduard Willem Zwart, Oss, NL;
Hubert Jan Jozef Loozen, Oss, NL;
Markus Wagener, Oss, NL;
Gerrit Veeneman, Oss, NL;
Eduard Willem Zwart, Oss, NL;
N.V. Organon, Oss, NL;
Abstract
This invention provides a compound, or its possible salt, having the formula, wherein: Rand 'Rare OH, optionally independently etherified or esterified; Z is —CHCH— or —C(R,R)—, wherein Rand Rare independently H, (1C-2C)alkyl or form together a spiro(3C-5C)cycloalkyl; Ris H, halogen, CF, or (1C-4C)alkyl; Rand Rare independently H, halogen, —CF, —OCF, (1C-8C)alkyl, hydroxy, (1C-8C)alkyloxy, aryloxy, aryl(1C-8C)alkyl, halo(1C-8C)alkyl, —O(CH)X, wherein X is halogen or phenyl and m=2-4; —O(CH)NRR, —S(CH)NRRor —(CH)NRR, wherein m=2-4 and wherein R, Rare independently (1C-8C)alkyl, (2C-8C)alkenyl, (2C-8C)alkynyl, or aryl, which alkyl, alkenyl and aryl can optionally be substituted with halogen, —CF, —OCF, —CN, —NO, —OH, (1C-8C)alkoxy, aryloxy, carboxyl, (1C-8C)alkylthio, carboxylate, (1C-8C)alkyl, aryl, aryl(1C-8C)alkyl or halo(1C-8C)alkyl; or Rand Rform a 3-8 membered ring structure, optionally substituted with halogen, —CF, —OCF, —CN, —NO, hydroxy, hydroxy(1C-4C)alkyl, (1C-8C)alkoxy, aryloxy, (1C-8C)alkylthio, carboxyl, carboxylate, (1C-8C)alkyl, aryl, aryl(1C-8C)alkyl, halo(1C-8C)alkyl.