The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2008
Filed:
Jan. 09, 2004
Benito Munoz, San Diego, CA (US);
Petpiboon Prasit, Rancho Santa Fe, CA (US);
Nicholas Simon Stock, San Diego, CA (US);
Benito Munoz, San Diego, CA (US);
Petpiboon Prasit, Rancho Santa Fe, CA (US);
Nicholas Simon Stock, San Diego, CA (US);
Merck + Co., Inc., Rahway, NJ (US);
Abstract
The present invention encompasses compounds of Formula I (I) or pharmaceutically acceptable salts thereof, wherein A is the base molecule of a propionic acid or acetic acid NSAID, or a derivative thereof, X is —COH, 1H-tetrazol-5-yl or 2H-tetrazol-5-yl and Rand Rare each independently selected from the group consisting of: Calkyl and Ccycloalkyl, as well as pharmaceutical composition comprising said compounds and methods of using said compounds. The compounds of the present invention lower the level of Aβand are therefore useful for preventing, delaying or reversing the progression of Alzheimer's Disease.