The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2008
Filed:
Aug. 29, 2003
Kimiya Maeda, Osaka, JP;
Hironobu Nagamori, Osaka, JP;
Hiroshi Nakamura, Osaka, JP;
Hisashi Shinkai, Osaka, JP;
Yasunori Suzuki, Osaka, JP;
Daisuke Takahashi, Osaka, JP;
Toshio Taniguchi, Osaka, JP;
Kimiya Maeda, Osaka, JP;
Hironobu Nagamori, Osaka, JP;
Hiroshi Nakamura, Osaka, JP;
Hisashi Shinkai, Osaka, JP;
Yasunori Suzuki, Osaka, JP;
Daisuke Takahashi, Osaka, JP;
Toshio Taniguchi, Osaka, JP;
Japan Tobacco Inc., Tokyo, JP;
Abstract
A dibenzylamine compound represented by the formula (1) wherein Rand Rare each a Calkyl group optionally substituted by halogen atoms and the like; R, Rand Rare each a hydrogen atom, a halogen atom and the like, or Rand Rmay form, together with carbon atoms bonded thereto, a homocyclic or heterocyclic ring optionally having substituent(s); A is—N(R) (R) and the like; ring B is an aryl group or a heterocyclic residue; Ris a hydrogen atom, a halogen atom, a nitro group, a Calkyl group and the like; n is an integer of 1 to 3, a prodrug thereof and a pharmaceutically acceptable salt thereof show selective and potent CETP inhibitory activity, and therefore, they can be provided as therapeutic or prophylactic agents for hyperlipidemia or arteriosclerosis and the like.