The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2008

Filed:

Nov. 23, 2005
Applicants:

Pu-ping LU, Foster City, CA (US);

David J. Morgans, Jr., Los Altos, CA (US);

Bing Yao, Hayward, CA (US);

Dashyant Dhanak, Collegeville, PA (US);

Steven David Knight, Collegeville, PA (US);

Inventors:

Pu-Ping Lu, Foster City, CA (US);

David J. Morgans, Jr., Los Altos, CA (US);

Bing Yao, Hayward, CA (US);

Dashyant Dhanak, Collegeville, PA (US);

Steven David Knight, Collegeville, PA (US);

Assignees:

Cytokinetics, Inc., South San Francisco, CA (US);

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/5025 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 211/78 (2006.01); C07D 211/82 (2006.01); C07D 211/70 (2006.01); C07D 211/90 (2006.01); C07D 211/72 (2006.01); C07D 211/84 (2006.01); C07D 213/84 (2006.01); C07D 213/72 (2006.01); C07D 213/78 (2006.01); C07D 213/46 (2006.01); C07D 213/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of modulating KSP kinesin activity in vitro comprising contacting KSP kinesin with at least one chemical entity chosen from compounds represented by Formula I: and pharmaceutically acceptable salts thereof, where the variables are as defined further herein.


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