The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2008

Filed:

Mar. 14, 2005
Applicants:

John Charles Kath, Waterford, CT (US);

Joel Morris, East Lyme, CT (US);

Samit Kumar Bhattacharya, Groton, CT (US);

Inventors:

John Charles Kath, Waterford, CT (US);

Joel Morris, East Lyme, CT (US);

Samit Kumar Bhattacharya, Groton, CT (US);

Assignee:

OSI Pharmaceuticals, New York, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/84 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 417/12 (2006.01); A61K 31/538 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R, R, R, R, R, m and p are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.


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