The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2008
Filed:
Sep. 11, 2001
H. David Humes, Ann Arbor, MI (US);
William H. Fissell, Whitmore Lake, MI (US);
Deborah A. Buffington, Ann Arbor, MI (US);
Evangelos Tziampazis, Plymouth, MI (US);
H. David Humes, Ann Arbor, MI (US);
William H. Fissell, Whitmore Lake, MI (US);
Deborah A. Buffington, Ann Arbor, MI (US);
Evangelos Tziampazis, Plymouth, MI (US);
RenaMed Biologics, Inc., Lincoln, RI (US);
Abstract
A device and a method of maintaining vascularization near an implant, especially a bioartificial hemofilter. By associating cells that excrete angiogenic factors with such an implant, vascularization to the tissue surrounding the implant can be maintained. In a bioartificial hemofilter, this facilitates filtrate transport to a collection fiber for drainage from the body. The cells can be genetically engineered, for example using an adenovirus vector encoding for vascular endothelial growth factor. Myoblasts and myotubes may be used in one embodiment of the present invention.