The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2008
Filed:
Feb. 07, 2005
Christian Betzel, Hamburg, DE;
Karsten Dierks, Hamburg, DE;
Gert Rapp, Hamburg, DE;
Rina-Netzwerk RNA Technologien GmbH, Berlin, DE;
Rapp OptoElectronic GmbH, Hamburg, DE;
Abstract
The invention relates to a method for monitoring the production of macromolecule crystals containing at least one fluorescence emitter, comprising the following steps: a) a solution volume with dissolved macromolecules of a molecule species containing at least one fluorescence emitter is subjected to conditions, which cause the macromolecules to crystallize to macromolecule crystals or which are expected to cause the macromolecules to crystallize to macromolecule crystals, b) the solution volume of step a is irradiated with coherent light, and the light scattered by the macromolecule crystals is detected in at least one defined spatial angle range by means for the detection scattered light, c) before, simultaneously with or after step b, the solution volume is irradiated with a light source, the light emission of which is suitable for exciting the fluorescence emitter, and the fluorescence light is detected by means for the detection of fluorescence light, and to a device for carrying-out the method.