The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2008

Filed:

Mar. 31, 2004
Applicants:

Liangqin Guo, Edison, NJ (US);

Shuwen He, Edison, NJ (US);

Tianying Jian, Westfield, NJ (US);

Yingjie Lai, Edison, NJ (US);

Jian Liu, Edison, NJ (US);

Ravi P. Nargund, East Brunswick, NJ (US);

Iyassu K. Sebhat, New York, NY (US);

Feroze Ujjainwalla, Scotch Plains, NJ (US);

Zhixiong YE, Princeton, NJ (US);

Jonathan R. Young, Kendall Park, NJ (US);

Inventors:

Liangqin Guo, Edison, NJ (US);

Shuwen He, Edison, NJ (US);

Tianying Jian, Westfield, NJ (US);

Yingjie Lai, Edison, NJ (US);

Jian Liu, Edison, NJ (US);

Ravi P. Nargund, East Brunswick, NJ (US);

Iyassu K. Sebhat, New York, NY (US);

Feroze Ujjainwalla, Scotch Plains, NJ (US);

Zhixiong Ye, Princeton, NJ (US);

Jonathan R. Young, Kendall Park, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); C07D 221/20 (2006.01); C07D 401/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Certain novel N-acylated spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.


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