The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2008

Filed:

Dec. 27, 1999
Applicants:

Jacques Dumas, Orange, CT (US);

Uday Khire, Hamden, CT (US);

Timothy B. Lowinger, Nishinomiya, JP;

Bernard Riedl, Branford, CT (US);

William J. Scott, Guilford, CT (US);

Roger A. Smith, Madison, CT (US);

Jill E. Wood, Hamden, CT (US);

Holia Hatoum-mokdad, Hamden, CT (US);

Jeffrey Johnson, Branford, CT (US);

Aniko Redman, Derby, CT (US);

Robert Sibley, North Haven, CT (US);

Inventors:

Jacques Dumas, Orange, CT (US);

Uday Khire, Hamden, CT (US);

Timothy B. Lowinger, Nishinomiya, JP;

Bernard Riedl, Branford, CT (US);

William J. Scott, Guilford, CT (US);

Roger A. Smith, Madison, CT (US);

Jill E. Wood, Hamden, CT (US);

Holia Hatoum-Mokdad, Hamden, CT (US);

Jeffrey Johnson, Branford, CT (US);

Aniko Redman, Derby, CT (US);

Robert Sibley, North Haven, CT (US);

Assignee:

Bayer Pharmaceuticals Corporation, West Haven, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/38 (2006.01); C07D 403/12 (2006.01); A61K 31/415 (2006.01);
U.S. Cl.
CPC ...
Abstract

The compounds are aryl and heteroaryl substituted heterocyclic ureas of the formula A—NH—C(O)—NH—B where A is the aryl or hetaryl substituted heterocyclic group and B is an aryl or heteroaryl moiety. The compounds inhibit raf kinase and are useful in the treatment of RAF kinase mediated diseases.


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