The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2008

Filed:

Jul. 16, 2004
Applicants:

Rajagopal Bakthavatchalam, Madison, CT (US);

Charles A. Blum, Westbrook, CT (US);

Harry Brielmann, Guilford, CT (US);

Stéphane DE Lombaert, Madison, CT (US);

Xiaozhang Zheng, Branford, CT (US);

Inventors:

Rajagopal Bakthavatchalam, Madison, CT (US);

Charles A. Blum, Westbrook, CT (US);

Harry Brielmann, Guilford, CT (US);

Stéphane De Lombaert, Madison, CT (US);

Xiaozhang Zheng, Branford, CT (US);

Assignee:

Neurogen Corporation, Branford, CT (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 31/519 (2006.01); C07D 401/04 (2006.01); C07D 405/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies


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