The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2008
Filed:
Apr. 05, 2004
Peter Blurton, Hitchin, GB;
Frank Burkamp, Bishops Stortford, GB;
Stephen Robert Fletcher, Bishops Stortford, GB;
A. Brian Jones, Saffron Walden, GB;
Edward Giles Mciver, Sawbridgeworth, GB;
Peter Blurton, Hitchin, GB;
Frank Burkamp, Bishops Stortford, GB;
Stephen Robert Fletcher, Bishops Stortford, GB;
A. Brian Jones, Saffron Walden, GB;
Edward Giles McIver, Sawbridgeworth, GB;
Merck Sharp & Dohme Limited, Hoddesdon, Hertfordshire, GB;
Abstract
The present invention provides a compound of formula (I): in which Ar and Rare phenyl or a heteroaromatic group, Ris generally hydrogen, Ris hydrogen or alkyl and X, Y and Z are generally CH or N as VR-1 antagonists; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising it; its use in therapy; use of it to manufacture medicaments to treat pain or inflammation; and methods of treating pain or inflammation