The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2008
Filed:
Jul. 18, 2005
John N. Feder, San Carlos, CA (US);
Randall C. Schatzman, Daly City, CA (US);
Pamela J. Bjorkman, Pasadena, CA (US);
Melanie Bennett, Pasadena, CA (US);
Jose Lebron, Pasadena, CA (US);
John N. Feder, San Carlos, CA (US);
Randall C. Schatzman, Daly City, CA (US);
Pamela J. Bjorkman, Pasadena, CA (US);
Melanie Bennett, Pasadena, CA (US);
Jose Lebron, Pasadena, CA (US);
Bio-Rad Laboratories, Inc., Hercules, CA (US);
California Institute of Technology, Pasadena, CA (US);
Abstract
The present invention relates to peptides and peptide analogues designed from HFE protein. In particular, it relates to peptides and peptide analogues designed from an alpha-1 region of HFE protein which lowers the binding affinity of transferrin receptor for transferrin. Such compounds mimic HFE protein function, and reduce iron uptake and/or accumulation by a cell.