The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2008
Filed:
Mar. 17, 2004
Norman R. Wainwright, Falmouth, MA (US);
Foster T. Jordan, Chapin, SC (US);
Frank C. Rumore, Lebanon, NJ (US);
Charles Balas, Jr., Madison, CT (US);
Norman R. Wainwright, Falmouth, MA (US);
Foster T. Jordan, Chapin, SC (US);
Frank C. Rumore, Lebanon, NJ (US);
Charles Balas, Jr., Madison, CT (US);
Charles River Laboratories, Inc., Wilmington, MA (US);
Abstract
The invention provides methods and compositions for the detection and/or quantification of a microbial contaminant, for example, a bacterial endotoxin or a glucan, in a sample. In particular, the invention provides a test cartridge useful in the practice of hemocyte lysate-based assays for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides methods of making and using such cartridges. In addition, the invention provides a rapid, sensitive, multi-step kinetic hemocyte lysate-based assay for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides a glucan-specific lysate that can be used in a variety of assay formats, including, for example, a test cartridge, optionally configured to perform a kinetic assay.