The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2008
Filed:
Dec. 01, 2000
Michael Houghton, Danville, CA (US);
Mark Selby, San Francisco, CA (US);
Sergio Abrignani, Vagliagli, IT;
Jens Martin Heile, Ludwigsburg, DE;
Derek O'hagan, Berkeley, CA (US);
Michael Houghton, Danville, CA (US);
Mark Selby, San Francisco, CA (US);
Sergio Abrignani, Vagliagli, IT;
Jens Martin Heile, Ludwigsburg, DE;
Derek O'Hagan, Berkeley, CA (US);
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Abstract
Described herein is a method of eliciting antibodies and neutralizing of binding antibodies against a hepatitis C virus (HCV) E1E2 or E2 antigen using HCV E2 or HCV E1E2 polypeptides and/or HCV E2 or E1E2 polynucleotides. Elicitation of anti-E2 antibodies and anti-E2 NOB antibodies can be used, inter alia, to provide model systems to optimize anti-E2 antibody responses and/or anti-E2 NOB antibody responses to HCV and to provide prophylactic or therapeutic treatment against HCV infection.