The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2008

Filed:

Jul. 14, 2003
Applicants:

Bruno Burdet, Baldersheim, FR;

August Ruettimann, Arlesheim, CH;

Inventors:

Bruno Burdet, Baldersheim, FR;

August Ruettimann, Arlesheim, CH;

Assignee:

DSM IP Assets B.V., Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for manufacturing a hydroxylated isoflavone of the formula (I) given in the description comprises re-acting an appropriately substituted 2-hydroxydeoxybenzoin of the formula (II), also given in the description, with a formic acid anhydride of the formula HCOOCOR3, wherein Rsignifies C-alkyl or various other groups as given in the description, in presence of a base or in a solvent which acts as a base, and if necessary promoting the ensuing hydrolysis of the so-produced acylated form of the hydroxylated isoflavone of the formula I by acidification. Of particular interest as products of this process are the 5,7dihydroxyisoflavones, e.g. genistein (5,7,4'-trihydroxyisoflavone). Isoflavones display many useful biochemical effects.


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