The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2008

Filed:

Jan. 29, 2003
Applicants:

Guyla Simig, Budapest, HU;

Tibor Mezei, Budapest, HU;

Marta Porcs-makkay, Pomaz, HU;

Attila Mandi, Budapest, HU;

Inventors:

Guyla Simig, Budapest, HU;

Tibor Mezei, Budapest, HU;

Marta Porcs-Makkay, Pomaz, HU;

Attila Mandi, Budapest, HU;

Assignee:

Les Laboratoires Servier, Courbevoie Cedex, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to 1-{2(S)-[1(S)-(ethoxycarbonyl)butylamino]propionyl}-(3aS,7aS)octahydroindol-2(S)-carboxylic acid of the Formula I and the t-butylamine salt of the Formula I' thereof free of contaminations derivable from dicyclohexyl carbodiimide, and a process for the preparation thereof. The invention also relates to new intermediates of the general Formula III (wherein R stands for lower alkyl or aryl lower alkyl). The compound of the Formula I—perindopril—is a known ACE inhibitor.


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