The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2008

Filed:

Sep. 09, 2003
Applicants:

Frank N. Chang, Dresher, PA (US);

Christopher R. Yonan, Plymouth Meeting, PA (US);

Inventors:

Frank N. Chang, Dresher, PA (US);

Christopher R. Yonan, Plymouth Meeting, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/453 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
Abstract

Proteins can be rapidly separated to a high degree of resolution by electrophoresis on polymeric membranes that have high protein binding capacity. The electrophoretic separation is carried out in a low conductivity, water-miscible organic solvent buffer. The low conductivity of the organic solvent buffer minimizes heat generation, and the water-miscible nature of the organic solvent buffer permits the analysis of hydrophobic and low molecular weight proteins as well as hydrophilic proteins. When electrophoresis is conducted under non-denaturing conditions, it allows the detection of enzymatic activities, protein-protein interactions and protein-ligand interactions.


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