The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2008

Filed:

Dec. 21, 2001
Applicants:

Barry Porter, Cambridge, GB;

Paul Gane, Cambridge, GB;

Raymond Beckett, Oxford, GB;

Kenneth Keavey, Oxford, GB;

Jac Wijkmans, Oxford, GB;

Lydia Saroglou, Oxford, GB;

Inventors:

Barry Porter, Cambridge, GB;

Paul Gane, Cambridge, GB;

Raymond Beckett, Oxford, GB;

Kenneth Keavey, Oxford, GB;

Jac Wijkmans, Oxford, GB;

Lydia Saroglou, Oxford, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 239/00 (2006.01); C07C 259/00 (2006.01); C07C 303/00 (2006.01); C07C 307/00 (2006.01); C07C 309/00 (2006.01); C07C 311/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula (I) and (IA) have antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH(═O) or of formula C(═O)NH(OH); Rrepresents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of formula N(OH)CH(═O), a hydroxy or amino group; Rrepresents a radical of formula R—(X)-(ALK)- wherein Rrepresents hydrogen, or an optionally substituted c-Calkyl, C-Calkenyl, C-Calkynyl, cycloalkyl, aryl, or heterocyclyl group, ALK represents a straight or branched divalent C-Calkylene, C-C6 ?alkenylene, or C-Calkynylene radical, and may be interrupted by one or more non-adjacent NH—, —O— or S— linkages, X represents NH—, —O— or S—, and m and n are independently 0 or 1; Rrepresents hydrogen, C-Calkyl, or benzyl; and Ris as defined in the specification.


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