The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2008
Filed:
Oct. 01, 2004
Fabio E. S. Souza, Mississauga, CA;
Jason E. Field, Mississauga, CA;
Ming Pan, Mississauga, CA;
Navindra J. Ramjit, Mississauga, CA;
Tharsika Tharmanathan, Markham, CA;
Tracey Jende-tindall, Aurora, CA;
Fabio E. S. Souza, Mississauga, CA;
Jason E. Field, Mississauga, CA;
Ming Pan, Mississauga, CA;
Navindra J. Ramjit, Mississauga, CA;
Tharsika Tharmanathan, Markham, CA;
Tracey Jende-Tindall, Aurora, CA;
Alphora Research Inc., Mississauga, Ontario, CA;
Abstract
Dronabinol, the tetrahydrocannabinol compound which comprises the active constituent of marijuana and is pharmaceutically useful as an antiemetic, is prepared by a process involving reaction of cis-menth-1-enc-3,8-diol with olivetol to form 1,3-dihydroxy-2-[(1R,6R)-6-(2-hydroxyprop-2-yl)-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene; and cyclizing the 1,3-dihydroxy-2-[(1R,6R)-6-(2-hydroxyprop-2-yl)-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene so formed to obtain dronabinol. A novel synthesis of cis-menth-1-ene-3,8-diol is also provided.