The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2008
Filed:
Jan. 25, 2006
Vladimir A. Dragan, Chester, NY (US);
John Richard Potoski, West Nyack, NY (US);
Wayne G. Mcmahon, Harriman, NY (US);
Jean Louise Helom, Hillsdale, NJ (US);
Xinxu Shi, Flushing, NY (US);
Vladimir A. Dragan, Chester, NY (US);
John Richard Potoski, West Nyack, NY (US);
Wayne G. McMahon, Harriman, NY (US);
Jean Louise Helom, Hillsdale, NJ (US);
Xinxu Shi, Flushing, NY (US);
Wyeth, Madison, NJ (US);
Abstract
The present invention provides processes for the preparation of substituted naphthylindole derivatives that can be used as inhibitors of plasminogen activator inhibitor-1(PAI-1). In certain embodiments of the invention, the processes involve reactions that include one or more of an Oppenauer oxidation, a Fischer indole synthesis, a methyl ether cleavage, or coupling a substituted methyltetrazole with a substituted naphthol.