The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2008
Filed:
May. 29, 2002
Yutaka Hanazono, Tochigi, JP;
Yasuji Ueda, Ibaraki, JP;
Yasushi Kondo, Kyoto, JP;
Yutaka Suzuki, Hyogo, JP;
Yutaka Hanazono, Tochigi, JP;
Yasuji Ueda, Ibaraki, JP;
Yasushi Kondo, Kyoto, JP;
Yutaka Suzuki, Hyogo, JP;
DNAVEC Research Inc., Ibaraki, JP;
Tanabe Seiyaku Co., Ltd., Osaka, JP;
Abstract
Highly efficient gene transfer into primate-derived embryonic stem (ES) cells has successfully been achieved by using a simian immunodeficiency virus vector (SIV) pseudotyped with VSV-G protein, which is a surface glycoprotein of vesicular stomatitis virus (VSV) The present invention provides simian immunodeficiency virus vectors for gene transfer to primate ES cells. The method for gene transfer to primate ES cells using the vectors of the present invention is useful in, for example, research into embryology and disease, clinical applications, and experimental models for primates. The method is also useful in assaying and screening for genes and reagents able to enhance the specific differentiation of tissues or cells, and which are useful in preparing desired cells or tissues differentiated from ES cells.