The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2008
Filed:
Oct. 16, 2002
Hisashi Narimatsu, Tsukuba, JP;
Niro Inaba, Hachioji, JP;
Toshie Iwai, Tsukuba, JP;
Abstract
Described are an enzyme having an activity to transfer N-acetylglucosamine to N-acetylgalactosaminyl group through a β1,3-linkage; nucleic acid coding for the enzyme; and method for diagnosis of a cancer and/or tumor, especially a cancer and/or tumor of a digestive organ using the expression amount of the gene of the enzyme as an index. A gene coding for a novel enzyme having an activity to transfer N-acetylglucosamine to N-acetylgalactosaminyl group through the β1,3-linkage was cloned from human colon and stomach cells, and the gene was sequenced. The enzyme was expressed, and a monoclonal antibody to the enzyme was prepared. Since this enzyme is not produced substantially or at all in cancer and/or tumor cells, especially in cancer or tumor cells of a digestive organ, the cancer and/or tumor may be diagnosed using the expression of the gene of the enzyme as an index.