The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2008
Filed:
Apr. 08, 2003
Applicants:
Yasmin A. Chandrasekher, Mercer Island, WA (US);
Patricia A. Mckernan, Seattle, WA (US);
Inventors:
Yasmin A. Chandrasekher, Mercer Island, WA (US);
Patricia A. McKernan, Seattle, WA (US);
Assignee:
ZymoGenetics, Inc., Seattle, WA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 38/21 (2006.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the anti-cancer activity of IL-24 polypeptide molecules. IL-24 is a cytokine involved in inflammatory processes and human disease. The present invention includes Use of IL-24 for decreasing proliferation of ovarian cancer cells, treating ovarian cancer, amongst other uses disclosed. IL-24 polypeptides can be administered alone, or can be fused to cytotoxic moieties, and can be administered in conjunction with radiation or chemotherapeutic agents.