The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2008

Filed:

May. 19, 2005
Applicants:

Jason Edward Field, Mississauga, CA;

Jan Oudenes, Aurora, CA;

Boris Ivanovich Gorin, Oakville, CA;

Ricardo Orprecio, Etobicoke, CA;

Fabio Eduardo Silva E Souza, Mississauga, CA;

Navindra Jainarine Ramjit, Hamilton, CA;

Emma-louise Moore, Mississauga, CA;

Inventors:

Jason Edward Field, Mississauga, CA;

Jan Oudenes, Aurora, CA;

Boris Ivanovich Gorin, Oakville, CA;

Ricardo Orprecio, Etobicoke, CA;

Fabio Eduardo Silva e Souza, Mississauga, CA;

Navindra Jainarine Ramjit, Hamilton, CA;

Emma-Louise Moore, Mississauga, CA;

Assignee:

Alphora Research Inc., Mississauga, Ontario, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/80 (2006.01);
U.S. Cl.
CPC ...
Abstract

An individual tetrahydrocannabinol isomer of interest is separated from a mixture containing two or more such isomers, by treating the mixture with an isocyanate or isothiocyanate of formula I:R—(CH)—N═C═X  (I)where R represents an aromatic ring optionally substituted with one or more electron withdrawing groups, n=0 or 1 and X is oxygen or sulphur; so as to produce a crystallizable THC carbamate of formula II: wherein X and R are as defined above, R' is a C-Calkyl group and the dotted lines indicate optional unsaturation including aromatic, separating the compound of formula II from solution in isolation of other THC derivatives, and hydrolyzing the compound of formula II to form the individual tetrahydrocannabinol isomer of interest.


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