The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2008

Filed:

Jul. 31, 2003
Applicants:

Rosanne Bonjouklian, Zionsville, IN (US);

Jose Eugenio DE Diego Gomez, Madrid, ES;

Alfonso DE Dios, Madrid, ES;

Chafiq Hamdouchi Hamdouchi, Carmel, IN (US);

Tiecho LI, Fishers, IN (US);

Beatriz Lopez DE Uralde Garmendia, Madrid, ES;

Michal Vieth, Carmel, IN (US);

Jeremy Schulenberg York, Indianapolis, IN (US);

Robert Dean Dally, Indianapolis, IN (US);

Miriam Filadelfa Del Prado Catalina, Madrid, ES;

Carlos Jaramillo Aguado, Madrid, ES;

Luisa Maria Martin-cabrejas, Madrid, ES;

Carlos Montero Salgado, Madrid, ES;

Sheila Pleite Selgas, Madrid, ES;

Concepcion Sanchez-martinez, Madrid, ES;

Timothy Alan Shepherd, Indianapolis, IN (US);

James Howard Wikel, Greenwood, IN (US);

Inventors:

Rosanne Bonjouklian, Zionsville, IN (US);

Jose Eugenio De Diego Gomez, Madrid, ES;

Alfonso De Dios, Madrid, ES;

Chafiq Hamdouchi Hamdouchi, Carmel, IN (US);

Tiecho Li, Fishers, IN (US);

Beatriz Lopez De Uralde Garmendia, Madrid, ES;

Michal Vieth, Carmel, IN (US);

Jeremy Schulenberg York, Indianapolis, IN (US);

Robert Dean Dally, Indianapolis, IN (US);

Miriam Filadelfa Del Prado Catalina, Madrid, ES;

Carlos Jaramillo Aguado, Madrid, ES;

Luisa Maria Martin-Cabrejas, Madrid, ES;

Carlos Montero Salgado, Madrid, ES;

Sheila Pleite Selgas, Madrid, ES;

Concepcion Sanchez-Martinez, Madrid, ES;

Timothy Alan Shepherd, Indianapolis, IN (US);

James Howard Wikel, Greenwood, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); A61K 31/428 (2006.01); C07D 277/68 (2006.01); C07D 235/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides kinase inhibitors of Formula I: wherein W represents inter alia imidazol, oxazol, pyrazol, thiazol as triazol, which are substituted by phenyl or thienyl. The disclosed compounds inhibit p-38 kinase and are useful in the treatment of metastasis or rheumatoid arthritis


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