The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2008
Filed:
Apr. 22, 2003
Albert Kudzovi Amegadzie, Indianapolis, IN (US);
Kevin Matthew Gardinier, Indianapolis, IN (US);
Erik James Hembre, Indianapolis, IN (US);
Jian Eric Hong, Carmel, IN (US);
Louis Nickolaus Jungheim, Indianapolis, IN (US);
Brian Stephen Muehl, Greenwood, IN (US);
David Michael Remick, Fishers, IN (US);
Michael Alan Robertson, Indianapolis, IN (US);
Kenneth Allen Savin, Indianapolis, IN (US);
Albert Kudzovi Amegadzie, Indianapolis, IN (US);
Kevin Matthew Gardinier, Indianapolis, IN (US);
Erik James Hembre, Indianapolis, IN (US);
Jian Eric Hong, Carmel, IN (US);
Louis Nickolaus Jungheim, Indianapolis, IN (US);
Brian Stephen Muehl, Greenwood, IN (US);
David Michael Remick, Fishers, IN (US);
Michael Alan Robertson, Indianapolis, IN (US);
Kenneth Allen Savin, Indianapolis, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
This application relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and its use as an inhibitor of the NK-1 subtype of tachykinin receptors, as well as a process for its preparation and intermediates therefor. (I) wherein: D is a C-Calkane-diyl; Ris phenyl, which is optionally substituted with one to three substitutents independently selected from the group consisting of halo, C-Calkyl, C-Calkoxy, cyano, difluoromethyl, trifluoromethyl, and trifluoromethoxy; Ris a radical selected from the group consisting of: (IA), (IB), (IC), (ID), (IE), (IF), (IG), (IH)