The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2008
Filed:
Oct. 08, 2003
Naoki Izumimoto, Kamakura, JP;
Koji Kawai, Oiso-machi, JP;
Kuniaki Kawamura, Kamakura, JP;
Morihiro Fujimura, Yokohama, JP;
Toshikazu Komagata, Kamakura, JP;
Naoki Izumimoto, Kamakura, JP;
Koji Kawai, Oiso-machi, JP;
Kuniaki Kawamura, Kamakura, JP;
Morihiro Fujimura, Yokohama, JP;
Toshikazu Komagata, Kamakura, JP;
Toray Industries, Inc., , JP;
Abstract
The invention provides a morphinan derivative of the Formula (I): wherein Ris methyl, cyclopropylmethyl or the like; Rand Rare hydroxy, methoxy, acetoxy or the like; both Y and Z are valence bonds, —C(═O)— or the like; X is C-Ccarbon chain (one of the carbon atoms may be substituted by oxygen, sulfur or nitrogen) constituting a part of the ring structure, or the like; (R)k is substituted or non-substituted benzene fused ring, carbonyl group or the like; Ris hydrogen or the like; Rand Rare bound to represent —O—, or the like, and Ris hydrogen or the like or a pharmaceutically acceptable acid addition salt thereof. The invention also provides a therapeutic or prophylactic agent for urinary frequency or urinary incontinence, comprising as an effective ingredient the morphinan derivative or the pharmaceutically acceptable acid addition salt thereof; a method for therapy or prophylaxis of the diseases.