The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2008
Filed:
Jul. 09, 2004
Guoping Zhao, Shanghai, CN;
Rui Heng Xu, Guangdong, CN;
Xinwei Wu, Guangdong, CN;
Changchun Tu, Jilin, CN;
Huai-dong Song, Shanghai, CN;
Yixue LI, Shanghai, CN;
Jinlin Hou, Guangdong, CN;
Jun Xu, Guangdong, CN;
Jun Min, Guangdong, CN;
Guoping Zhao, Shanghai, CN;
Rui Heng Xu, Guangdong, CN;
Xinwei Wu, Guangdong, CN;
Changchun Tu, Jilin, CN;
Huai-Dong Song, Shanghai, CN;
Yixue Li, Shanghai, CN;
Jinlin Hou, Guangdong, CN;
Jun Xu, Guangdong, CN;
Jun Min, Guangdong, CN;
Chinese National Human Genome Center at Shanghai, Shanghai, CN;
Abstract
Severe Acute Respiratory Syndrome ('SARS') is a human respiratory disease of recent origin, widespread infectivity, recurring incidence, and significant mortality. Although there is abundant evidence suggesting that the coronavirus responsible for the disease ('SARS-CoV') evolves during an outbreak, there is currently little data on the earliest strains of this coronavirus. The present invention is directed to the characterization of the genomic RNA sequences of these earliest SARS coronaviruses, to the identification of nucleotide positions within the SARS-CoV genomic RNA that are characteristic of the different evolutionary stages of the coronavirus, to kits based on these positions for use in diagnosis of the disease in patients, and for the development of vaccines to the disease based on the lowered virulence and contagiousness of these earliest strains of SARS-CoV.