The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2008

Filed:

Feb. 25, 2003
Applicants:

Rodolfo Cadilla, Durham, NC (US);

Brad Richard Henke, Durham, NC (US);

Millard H. Lambert, Iii, Durham, NC (US);

Guangcheng Kevin Liu, San Diego, CA (US);

Jennifer Susan Smith, Durham, NC (US);

Inventors:

Rodolfo Cadilla, Durham, NC (US);

Brad Richard Henke, Durham, NC (US);

Millard H. Lambert, III, Durham, NC (US);

Guangcheng Kevin Liu, San Diego, CA (US);

Jennifer Susan Smith, Durham, NC (US);

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); A61K 31/42 (2006.01); A61K 31/445 (2006.01); A61K 31/425 (2006.01); C07D 239/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula (1) or a pharmaceutically acceptable salt, solvate, acid isostere, or hydrolyzable ester thereof, are disclosed. Methods of making and using the compounds are also disclosed. In particular methods for treating diseases or conditions associated with one or more of human PPAR alpha, gamma, or delta ('hPPARs') comprising administration of a therapeutically effective amount of a compound of formula (1), are disclosed


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